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  • Oncologia

    Lifestyle and Risk of Colorectal Cancer

    There is a clear prevalence of colorectal cancer in western countries, which can be easily explained with an association between this type of cancer and lifestyle. Through a prospective study performed in Denmark, more than 55,000 people between 50 and 64 years of age have been examined, determining the association between a simple index representing lifestyle and the incidence of this particular cancer.

    MedNews - Mar, 10 Aprile 2012
    http://mn.medsurfnews.com/

  • Neurologia

    Vitamin B and Cognitive Processes

    According to many epidemiological studies, we know that the increase in plasmatic homocysteine is associated with a decrease in cognitive functions, so researchers consequently wondered whether vitamin B supplementation, capable to decrease the levels of homocysteine, can avoid or delay cognitive decrease.

    MedNews - Mar, 10 Aprile 2012
    http://mn.medsurfnews.com/

  • Infettivologia

    Improving Adherence to Antiretroviral Therapy for Youth Living with HIV/AIDS: A Pilot Study Using Personalized, Interactive, Daily Text Message Reminders

    To evaluate the feasability, acceptability, and preliminary efficacy of short message service (SMS) or text message reminders to improve adherence to antiretroviral therapy for youth living with HIV/AIDS, researchers conducted a prospective pilot study using a pre–post design from 2009 to 2010 at a community-based health center providing clinical services to youth living with HIV/AIDS. Results showed that personalized, interactive, daily SMS reminders were feasible and acceptable, and they significantly improved self-reported adherence. Larger controlled studies are needed to determine the impact of this intervention on antiretroviral therapy adherence and other related health outcomes for youth living with HIV/AIDS.

    Journal of Medical Internet Research - JMIR - Mar, 10 Aprile 2012
    http://www.jmir.org

  • Medicina generale

    Medical Web Radio: What Gut Microbiota is learning to us regarding medicine?

    The latest MD-FM insight will be devoted to the understanding of what “Gut Microbiota” is and why this new “organ” has recently been shown to play a central role in Medicine.

    md-fm.com - Mar, 10 Aprile 2012
    http://www.md-fm.com

  • Oncologia

    Breast cancer patients and long term treatment-related side effects

    More than 60 percent of breast cancer survivors report at least one treatment-related complication even six years after their diagnosis, according to a new study led by a researcher from the Perelman School of Medicine at the University of Pennsylvania. The findings are part of a special issue of CANCER devoted to exploring the physical late effects of breast cancer treatment and creating strategies to prevent, monitor for, and treat these conditions in the nation's 2.6 million survivors of the disease.

    ecancer - Mar, 10 Aprile 2012
    http://ecancer.org

  • Epatologia

    New biomarker to identify hepatitis B-infected patients at risk for liver cancer

    Hepatitis B-infected patients with significantly longer telomeres were found to have an increased risk of getting liver cancer compared to those with shorter ones, according to findings presented by researchers at Jefferson's Kimmel Cancer Center at the American Association for Cancer Research (AACR) Annual Meeting 2012. A strong correlation between telomere length and non-cirrhotic hepatocellular carcinoma (HCC), a liver cancer commonly caused from hepatitis B and C viral infections, could help physicians better stratify the hepatitis B population in an effort to better prevent and treat the disease.

    ecancer - Mar, 10 Aprile 2012
    http://ecancer.org

  • Immunologia

    Prevalence of collagen VII-specific autoantibodies in patients with autoimmune and inflammatory diseases

    Autoimmunity to collagen VII is typically associated with the skin blistering disease epidermolysis bullosa acquisita (EBA), but also occurs occasionally in patients with systemic lupus erythematosus or inflammatory bowel disease. A study developed an immunoassay for assessing the presence of autoantibodies against collagen VII in large cohorts of patients and healthy donors.

    BioMed Central - Mar, 10 Aprile 2012
    http://www.biomedcentral.com

  • Medicina generale

    Do you think it's a disease? A survey of medical students

    Students were mostly concordant on what conditions should be classified as "disease". They were more likely to classify synonyms as 'disease' if the label was medical. These are the outcome of a survey, aimed at determining how medical students classify a range of conditions they might encounter in their professional lives and whether a different name for a condition would influence their decision in the categorisation of the condition as a 'disease' or 'not a disease'.

    BioMed Central - Mar, 10 Aprile 2012
    http://www.biomedcentral.com

  • Oncologia

    KRAS Gene Mutation and Amplification Status Affects Sensitivity to Antifolate Therapy

    Testing patients with non-small cell lung cancer for both mutations and amplifications of the KRAS gene prior to therapy may help to predict response to treatment with antifolates, according to the updated results of a preclinical study presented at the AACR Annual Meeting 2012, held here March 31 – April 4.

    American Association for Cancer Research - AACR - Mar, 10 Aprile 2012
    http://www.aacr.org

  • Allergologia

    Allergen-specific immunotherapy reduced to three injections

    In a recent article in The Journal of Allergy and Clinical Immunology, Senti et al. could reduce the number of allergen injections to three by enhancing antigen presentation. Firstly, the allergen was injected directly into lymph nodes. Secondly, the allergen, recombinant cat dander allergen Fel d 1, was fused with an intracellular translocation sequence and with an invariant chain to enhance presentation via MHC class II to CD4 T cells.

    American Academy of Allergy, Asthma and Immunology - Mar, 3 Aprile 2012
    http://www.aaaai.org

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