Ematologia

Tranexamic Acid after Severe Injuries

The use of tranexamic acid during surgeries is associated with less blood losses and less needs of transfusions. According to this statement, with a randomized trial, partly sponsored by pharmaceutical industry (CRASH-2: Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage 2) the efficacy of this antifibrinolytic has been assessed in 20,211 patients experimenting injuries and bleeding risk. The drug (or placebo) has been given within the first 8 hours after injury; the dose of tranexamic acid has been 1 g within the first 10 minutes, followed by a slow infusion of 1 g during the following 8 hours.
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 http://mn.medsurfnews.com/contents/en/6082/display/tranexami...

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