Cardiologia

Peripheral Arterial Disease and Progression of Coronary Atherosclerosis

Peripheral arterial disease is associated with adverse cardiovascular outcomes. The impact of concomitant PAD on coronary atherosclerosis progression in patients with coronary artery disease has not been well established. A recent study investigates the burden and progression of coronary atherosclerosis in 3,479 patients with coronary artery disease with (n = 216) and without (n = 3,263) concomitant PAD who participated in 7 clinical trials that employed serial intravascular ultrasound imaging. Patients with concomitant PAD harbor more extensive and calcified coronary atherosclerosis, constrictive arterial remodeling, and greater disease progression. These changes are likely to contribute to adverse cardiovascular outcomes.
Approfondisci

 http://content.onlinejacc.org/cgi/content/short/57/10/1220?r...

Journal of the American College of Cardiology