Colonproctologia

CT Colonography Screening

CT colonography, inappropriately defined by someone as “virtual colonoscopy”, has been, up to now, evaluated as a screening means in trials concerning above all populations with a high risk of intestinal cancer. In this European trial, 937 subjects with a high risk for tumours (family history for colorectal cancer, personal history of colorectal adenomas, positive occult blood test) have undergone CT colono-graphy followed, in the same day, by colonoscopy; endoscopists performed endoscopy in blind, which was abolished only in case of results contrasting with CT and endoscopy. The searched main outcome was the presence of an adenoma of at least 6 mm of diameter, with suspected characteristics. Compared with colonoscopy, CT colonography presented a positive predictive value of 62% and a negative pre-dictive value of 96%.
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