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While the role of hydroxymethyl glutaryl coenzyme A reductase inhibitors (statins) in secondary prevention of cardiovascular (CV) events and mortality is established, their value for primary prevention is less clear. To clarify the role of statins for patients without CV disease, we performed a meta-analysis of randomized controlled trials (RCTs).
Archives of Internal Medicine (Cardiologia) - Mar, 5 Dicembre 2006
http://archinte.ama-assn.org/
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Obesity is associated with increased risk of atrial fibrillation (AF), but it is unknown whether the association differs by duration or persistence of AF. It is also unknown to what extent cardiovascular risk factors may mediate this association.
Archives of Internal Medicine (Cardiologia) - Mar, 5 Dicembre 2006
http://archinte.ama-assn.org/
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Physical activity is associated to a decrease in cardiovascular risk, but how much activity is necessary to obtain this effect in childhood? In order to answer to this question a cross-sectional study was performed (The European Youth Heart Study) involving 915 girls and 817 boys between 9 and 15 years of age, enrolled in Denmark, Estonia and Portugal.
MedNews (Cardiologia) - Lun, 4 Dicembre 2006
http://mn.medsurfnews.com/
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Hospitals have a variety of strategies to reduce the time from arrival at the hospital to intracoronary balloon inflation (door-to-balloon time) for patients who have acute myocardial infarction with ST-segment elevation. In a study of 365 hospitals, 28 institutional strategies were identified with the use of a field-tested questionnaire. These strategies were correlated with door-to-balloon times for individual patients as reported to the Centers for Medicare and Medicaid Services. Six strategies were associated with a significant reduction in the door-to-balloon time. The use of these strategies may improve outcomes for patients.
New England Journal of Medicine (Cardiologia) - Gio, 30 Novembre 2006
http://www.nejm.org
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A longer infusion time for anthracycline administration appears to reduce the risk of cardiac failure, suggests a new review.
Medscape (Cardiologia) - Mer, 29 Novembre 2006
http://www.medscape.com
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Erythropoietin (EPO) is a hypoxia-induced hormone produced in the kidneys that stimulates hematopoiesis in the bone marrow. However, recent studies have also shown important nonhematopoietic effects of EPO.
Journal of the American College of Cardiology (Cardiologia) - Mer, 29 Novembre 2006
http://content.onlinejacc.org/
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Intravenous myocardial contrast echocardiography (MCE) is a recently developed technique for assessment of myocardial perfusion. Up to now, many studies have demonstrated that the sensitivity and specificity of qualitative assessment of myocardial perfusion by MCE in patients with acute and chronic ischemic heart disease are comparable with other techniques such as cardiac scintigraphy and dobutamine stress echocardiography.
Journal of the American College of Cardiology (Cardiologia) - Mer, 29 Novembre 2006
http://content.onlinejacc.org/
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The role of late enhancement cardiovascular magnetic resonance imaging (LE-CMR) for the diagnosis of right ventricular infarction (RVI).
Journal of the American College of Cardiology (Cardiologia) - Mer, 22 Novembre 2006
http://content.onlinejacc.org/
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The purpose of this study was to examine the potential of intravascular gadolinium (Gd)-chelates in discriminating acute from chronic myocardial infarctions (MIs).
Journal of the American College of Cardiology (Cardiologia) - Mer, 22 Novembre 2006
http://content.onlinejacc.org/
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Repairing a damaged myocardium with "universal donor" cells — using stem cells from an unrelated donor, or even an animal — is approaching clinical trials, after successful results of early trials being conducted at McGill University in Montreal, Quebec, Canada.
Medscape (Cardiologia) - Mar, 21 Novembre 2006
http://www.medscape.com