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Keeping pace with the stream of new data and evolving evidence on which guideline recommendations are based is an ongoing challenge to timely development of clinical practice guidelines. In an effort to respond promptly to new evidence, the American College of Cardiology Foundation/American Heart Association (ACCF/AHA) Task Force on Practice Guidelines (Task Force) has created a "focused update" process to revise the existing guideline recommendations that are affected by the evolving data or opinion.
Journal of the American College of Cardiology - Mar, 18 Ottobre 2011

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Substantial evidence suggests that a large portion of the population have suboptimal levels of vitamin D, which may adversely affect the cardiovascular (CV) system. An article reviews the evidence that vitamin D deficiency is associated with incident CV disease events, as well as evidence that vitamin D supplementation is associated with reduction in CV diseases.
Journal of the American College of Cardiology - Mar, 27 Settembre 2011

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Alterations in gene expression in peripheral blood cells have been shown to be sensitive to the presence and extent of coronary artery disease (CAD). A non-invasive blood test that could reliably assess obstructive CAD likelihood would have diagnostic utility. The short-term outcomes and feasibility of modular stent-graft implantation for abdominal aortic aneurysm (AAA) have been demonstrated. However, the long-term outcomes remained to be observed. The article shows images of a modular stent-graft implanted on a 69-year-old man with exacerbating abdominal pain for his AAA.
Journal of the American College of Cardiology - Lun, 28 Marzo 2011

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Peripheral arterial disease is associated with adverse cardiovascular outcomes. The impact of concomitant PAD on coronary atherosclerosis progression in patients with coronary artery disease has not been well established. A recent study investigates the burden and progression of coronary atherosclerosis in 3,479 patients with coronary artery disease with (n = 216) and without (n = 3,263) concomitant PAD who participated in 7 clinical trials that employed serial intravascular ultrasound imaging. Patients with concomitant PAD harbor more extensive and calcified coronary atherosclerosis, constrictive arterial remodeling, and greater disease progression. These changes are likely to contribute to adverse cardiovascular outcomes.
Journal of the American College of Cardiology - Lun, 7 Marzo 2011

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A present paper provides an overview of the current available evidence on the use of antithrombotic therapy in elderly patients with the primary focus on treatment of coronary artery disease.
Journal of the American College of Cardiology - Mar, 9 Novembre 2010

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Patients with HF with higher depressive symptoms and norepinephrine exhibited increased peripheral blood mononuclear cell CTX to isoproterenol to mild exercise, suggesting greater β-adrenergic sensitivity. Increased immune migration in patients with HF who have elevated depressive symptoms could be associated with cardiac remodeling and HF disease progression.
Journal of the American College of Cardiology - Mar, 9 Novembre 2010

http://content.onlinejacc.org/
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Routine quantification of CAC progression cannot currently be recommended in clinical practice. First, standards of how CAC progression should be defined and assessed need to be developed. In addition, there remains a need for further studies analyzing the effect of other cardiac therapies on CAC progression and cardiac outcomes.
Journal of the American College of Cardiology - Mar, 2 Novembre 2010

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A review summarizes the general measures, ventilation strategies, vasoactive substances, and surgical as well as mechanical approaches that are currently used or actively investigated in the treatment of the acutely failing RV.
Journal of the American College of Cardiology - Lun, 25 Ottobre 2010

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Transient use of small amounts of corticosteroids shortly after AF ablation may be effective and safe for preventing not only immediate AF recurrences but also atrial fibrillation recurrences during the mid-term follow-up period after pulmonary vein isolation.
Journal of the American College of Cardiology - Lun, 25 Ottobre 2010

http://content.onlinejacc.org/
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Severe QRS prolongation, before or after pulmonary valve replacement, and the absence of a reduction in QRS duration after PVR, are major determinants of adverse outcome during long-term follow-up of patients with tetralogy of Fallot.
Journal of the American College of Cardiology - Lun, 25 Ottobre 2010

http://content.onlinejacc.org/