Urologia 

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  • Germs Behind Urinary Tract and Drug Resistance

    E. coli bacteria's resistance to ciprofloxacin (Cipro), the most widely prescribed antimicrobial for urinary tract infections in the United States, increased five-fold between 2000 and 2010, according to a new study.

    Medline Plus (Urologia) - Lun, 7 Maggio 2012
    http://www.nlm.nih.gov/medlineplus

  • Fructose and Gout Risk

    It is well known that the use of fructose increases the levels of uric acid, being a risk for gout onset when it is used as the only or the main form of sweetener. This occurs in males, but is the same thing valid also for women? In order to answer this question, some questionnaires have been used among the about 79,000 participants to the Nurses’ Health Study, followed for 22 years and without gout at the beginning of the trial.

    MedNews (Urologia) - Lun, 16 Aprile 2012
    http://mn.medsurfnews.com/

  • Metabotropic glutamate receptor 5 (mGluR5) regulates bladder nociception

    Interstitial cystitis/painful bladder syndrome (IC/PBS), is a severely debilitating chronic condition that is frequently unresponsive to conventional pain medications. The etiology is unknown, however evidence suggests that nervous system sensitization contributes to enhanced pain in IC/PBS. Data suggest that mGluR5 modulates both inflammatory and non-inflammatory bladder nociception, and highlight the therapeutic potential for mGluR5 antagonists in the alleviation of bladder pain.

    Molecular Pain (Urologia) - Mar, 27 Marzo 2012
    http://www.molecularpain.com

  • Pregabalin in Chronic Prostatitis and in Pelvic Pain

    An invalidating condition about which we know a few remedies is represented by chronic pelvic pain associated with prostatitis, where, in the absence of infections, a neuropathic mechanism is hypothesized. In order to evaluate this hypothesis, a multicentric trial, sponsored by the US national health service, has been performed, involving 324 males (averagely 47 years of age; 79% white) presenting chronic pelvic pain attributed to prostatitis from an average period of 9 years.

    MedNews (Urologia) - Mar, 21 Febbraio 2012
    http://mn.medsurfnews.com/

  • PSA Screening and Mortality

    In 2008, the U.S. Preventive Services Task Force has concluded that there is no sufficient evidence to evaluate whether benefits or damages caused by PSA screening prevail in males below 75 years of age, while the performance of the exam beyond this age has not been advised. At that age, many trials had not finished yet, so now a meta-analysis has been performed, examining some wide trials finished in the last 2 years: 390,000 asymptomatic subjects (between 45 and 80 years of age) have undergone PSA dosage associated or not with rectal digital exploration.

    MedNews (Urologia) - Lun, 13 Febbraio 2012
    http://mn.medsurfnews.com/

  • Study predicts rise in global lower urinary tract problems

    Around 2.3 billion adults worldwide could potentially suffer from at least 1 less urinary tract symptom by 2018, new research suggests. The study, to be presented in the October issue of the British Journal of Urology International (BJUI), demonstrates how the number of people aged 20 and over that are affected by urinary and bladder symptoms represents an 18% jump in the last 10 years. Europe, however, will report the lesser increase in number of cases compared with other regions around the globe.

    Cordis - Community Research and Development Information Service (Urologia) - Mar, 4 Ottobre 2011
    http://cordis.europa.eu

  • Understanding urine output in critically ill patients

    The aim of the review is to discuss the mechanisms of diuresis regulation which may help interpreting the urine output in critically ill patients and the appropriate treatment to be initiated in face of changes in urine output.

    SpringerOpen Journal (Urologia) - Lun, 30 Maggio 2011
    http://www.springeropen.com

  • Warfarin and Urinary Antibiotics

    Hemorrhagic episodes are a frequent side effect in older patients treated with warfarin, and the interaction between warfarin and other drugs can increase bleeding risk. With a recent case-control trial, performed using some databases from Ontario, Canada, the bleeding risk at the upper gastrointestinal tract in patients treated with urinary antibiotics and under continuative therapy with warfarin has been examined. The sample was made up of 134,637 patients ≥ 66 years of age taking warfarin for at least 180 continuative days. In this cohort, 45,972 subjects had received the prescription of at least one antibiotic.

    MedNews (Urologia) - Lun, 23 Maggio 2011
    http://mn.medsurfnews.com/

  • Antibiotics for PSA

    When there are slightly higher PSA values, some clinicians treat the patient with antibiotics, aiming at acting against a possible prostatitis which increases those values and also to obtain a reassurance “ex juvantibus”: the decrease of PSA would show the absence of cancers. In order to verify that this approach can be shared, a randomized trial has been performed in Brazil: 98 asymptomatic males (between 50 and 75 years of age) with PSA levels between 2.5 and 10 ng/dl, affected by probable prostatitis (increase in leukocytes in urines after prostatic massage or presence of urethral secretion) and with a normal rectal exploration have been enrolled.

    MedNews (Urologia) - Lun, 4 Aprile 2011
    http://mn.medsurfnews.com/

  • Testosterone Supplementation

    The levels of testosterone decrease with age, but the usefulness of an integrative administration is still under discussion. With this randomized trial, some English researchers have enrolled 274 74-year-old males, with plasmatic testosterone levels ≤ 345 ng/dl (or with free testosterone levels ≤ 7.2 ng/dl). For a period of 6 months, they have been treated with a transdermal testosterone-based gel or placebo.

    MedNews (Urologia) - Lun, 7 Marzo 2011
    http://mn.medsurfnews.com/

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