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Acetylsalicylic acid sensitivity is common in patients with nasal polyposis, and that patients with extensive and long-term nasal polyposis with multiple polyp operations should be evaluated for the presence of acetylsalicylic acid sensitivity. These are the conclusions of a study evaluating Sixty-eight patients with nasal polyps.
American Academy of Allergy, Asthma and Immunology - Lun, 7 Maggio 2012
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In a recent article in The Journal of Allergy and Clinical Immunology, Senti et al. could reduce the number of allergen injections to three by enhancing antigen presentation. Firstly, the allergen was injected directly into lymph nodes. Secondly, the allergen, recombinant cat dander allergen Fel d 1, was fused with an intracellular translocation sequence and with an invariant chain to enhance presentation via MHC class II to CD4 T cells.
American Academy of Allergy, Asthma and Immunology - Mar, 3 Aprile 2012
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In a manuscript in The Journal of Allergy and Clinical Immunology (JACI), Sumino et al and the American Lung Association Asthma Clinical Research Centers examined the utility of the MCT on asthmatics who are on controller medications. The researchers evaluated the sensitivity (percentage of asthma patients who are correctly identified as having asthma) and specificity (percentage of healthy people who are correctly identified as not having asthma) of MCT in 126 patients with asthma diagnosed by a physician, and 93 normal healthy individuals.
American Academy of Allergy, Asthma and Immunology - Mar, 3 Aprile 2012
http://www.aaaai.org
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Assessing asthma control in children is particularly challenging: impulse oscillometry (IOS) being a new non-invasive technique has been increasingly used for the diagnosis of asthma. IOS is effort-independent and able to separately quantify the obstructions in proximal and distal airways, but has not previously been utilized to assess asthma control in children. In a recent article in The Journal of Allergy and Clinical Immunology (JACI), Shi et al. measured IOS in 101 children (6-17 yrs) with mild-to-moderate asthma. In a recent article in The Journal of Allergy and Clinical Immunology (JACI), Shi et al. measured IOS in 101 children (6-17 yrs) with mild-to-moderate asthma.
American Academy of Allergy, Asthma and Immunology - Mar, 20 Marzo 2012
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Respiratory syncytial virus (RSV) and human rhinovirus (HRV) are the most common viruses associated with infant acute respiratory infections (ARI). Both RSV and HRV lower respiratory tract infections (LRTIs) during infancy and early childhood are associated with an increased risk of asthma later in childhood.
American Academy of Allergy, Asthma and Immunology - Mar, 13 Marzo 2012
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In an upcoming issue of The Journal of Allergy and Clinical Immunology (JACI), Nicholson et al evaluated the effects of an anti-IL-13 blocking antibody compared with placebo on repeated nasal allergen challenge (NAC) responses in hay fever patients out of season. Nasal challenge models with serial non-invasive sampling have considerable potential to study the molecular basis of mucosal inflammatory responses. The authors conclude that nasal challenge models can also be used to predict responders and monitor effects of specific therapy for allergy and asthma.
American Academy of Allergy, Asthma and Immunology - Lun, 18 Luglio 2011
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The relationship between breastfeeding and allergic diseases is a subject of debate. The possibility that this relationship may vary by individual genetic susceptibility has not been explored. In an upcoming issue of The Journal of Allergy and Clinical Immunology (JACI), Hong et al. examined the effect of breastfeeding and gene-breastfeeding interactions on food sensitization (FS) in 960 children from an inner-city U.S. prospective birth cohort. FS was defined as specific IgE ≥0.35 kUA/L to any of eight common food allergens.
American Academy of Allergy, Asthma and Immunology - Lun, 27 Giugno 2011
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Anaphylactic reactions to diphtheria, tetanus, and pertussis vaccines (DTaP and Tdap) are rare. In an upcoming issue of The Journal of Allergy and Clinical Immunology, Kattan et al report a case series of 8 children who presented to their food allergy referral center from 2007-10 with a history of anaphylaxis to booster doses of these vaccines.
American Academy of Allergy, Asthma and Immunology - Mar, 14 Giugno 2011
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A unique landmark study, that defines the long-term natural history of EoE and the key role of allergy, is an important set of findings suggesting that EoE morbidity is greater among patients with atopy. Taken one step further, data support the need for allergy testing among patients with EoE, as identifying patients with atopy will not only assist in dietary management, but will help identify those at greatest risk for persistent disease.
American Academy of Allergy, Asthma and Immunology - Mar, 14 Giugno 2011
http://www.aaaai.org
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In a recent issue of The Journal of Allergy and Clinical Immunology, Ozturk et al assessed for the first time the effectiveness of oral methylprednisolone (MP) as an adjunct to antibiotics in the treatment of 48 children and adolescents with CRS without nasal polyposis in a double-blind placebo controlled study. Short-term oral MP seems to provide added benefit to treatment with antibiotics for children with CRS.
American Academy of Allergy, Asthma and Immunology - Mar, 7 Giugno 2011
http://www.aaaai.org