Farmacologia

Side Effects of Statins

With a trial based on the English QResearch database, over 2 million subjects between 30 and 84 years of age have been examined; out of these, about 225,000 had recently been under continuative therapy with statins: 160,000 with simvastatin, 50,000 with atorvastatin and 15,000 with pravastatin, rosuvastatin or fluvastatin. The use of statins was associated, in a statistically significant way, with a lower risk of esophageal cancer, but with a higher risk of liver disease (an increase in ALT of about three times higher than the normal value), of myopathy (discovered clinically or through CK levels measurement four times higher than the highest normal value), of acute renal failure and cataract.
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 http://mn.medsurfnews.com/contents/en/6081/display/side-effe...

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