Dermatology 

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  • Strategies for Treatment With Anti–Tumor Necrosis Factor Agents in Psoriasis

    Psoriasis is a very common, chronic, immune-mediated disease that commonly presents in young patients.

    Archives of Dermatology (Dermatology) - Mon, 22 February 2010
    http://archderm.ama-assn.org/

  • Skin Abscesses and Antibiotics

    The incidence of skin and soft-tissue infections has dramatically increased in the USA during the last decade and most of these infections have been caused by a methicillin-resistant Staphylococcus aureus (MRSA). Even if the drainage of abscess infections is the most indicated treatment, someone also considers the adding of antibiotics, which are instead not advised by other physicians dealing with infectious diseases.

    MedNews (Dermatology) - Fri, 12 February 2010
    http://mn.medsurfnews.com/

  • Basal Cell Nevus Syndrome

    A 53-year-old man with basal cell nevus syndrome sought a different treatment modality than surgical excisions for his numerous basal cell carcinomas. He was referred to a clinical trial involving an oral antagonist of the PTCH signaling pathway. The results were promising.

    Archives of Dermatology (Dermatology) - Fri, 22 January 2010
    http://archderm.ama-assn.org/

  • Clinically Amyopathic Dermatomyositis

    I first started caring for patients with dermatomyositis (DM) skin disease under the guidance of James N. Gilliam, MD, while serving as an immunodermatology research fellow in the Department of Dermatology at UT Southwestern Medical Center in Dallas, Texas, in 1976. Among the patients I encountered working with him were individuals who for atypically prolonged periods (>6 months) displayed hallmark cutaneous lesions of DM as an isolated clinical finding. That such patients had not developed the expected systemic manifestation of proximal muscle weakness during this time frame made them unusual. At that time, such patients were commonly referred to by dermatologists as having "DM sine myositis." Such patients were not then recognized by nondermatologists at that time as having a form of DM because they did not meet the Bohan classification criteria for DM.

    Archives of Dermatology (Dermatology) - Fri, 22 January 2010
    http://archderm.ama-assn.org/

  • Managing comorbid disease in patients with psoriasis

    Psoriasis is a common and severe disease, impairing patients’ quality of life to an extent similar to other major diseases such as cancer or diabetes mellitus Psoriasis is a systemic disease: Th17 cells are important effector cells and biomarkers of systemic inflammation are raised Several important diseases including psoriatic arthritis, metabolic syndrome, Crohn’s disease, cancer, and depression are associated with psoriasis Life expectancy is reduced by about four years in patients with severe psoriasis, primarily owing to their increased cardiovascular risk Physicians in primary and secondary care need to detect developing comorbidities early, using validated questionnaires (to detect psoriatic arthritis) and proper monitoring Treatment decisions must take into account patients’ comorbidities (to identify contraindications) and comedication (to avoid drug interactions)

    British Medical Journal (Dermatology) - Fri, 15 January 2010
    http://www.bmjjournals.com

  • Lack of Lower Extremity Hair Not a Predictor for Peripheral Arterial Disease

    Peripheral arterial disease (PAD) afflicts 8 to 12 million Americans, but nearly 75% of them are asymptomatic.1 Physicians rely on history and physical examination to determine which patients require further evaluation. Physical findings that have been associated with arterial disease include a unilaterally cool extremity, skin atrophy and lack of hair, and abnormal pedal pulses, among others.

    Archives of Dermatology (Dermatology) - Fri, 15 January 2010
    http://archderm.ama-assn.org/

  • Relevance of D-dimer Testing in Patients with Venous Malformations

    Venous malformations (VMs) are among the most common vascular malformations, second in frequency only to port-wine stains, and they are the most common vascular malformations seen in multidisciplinary vascular anomalies referral centers.1 They are structural anomalies of the venous vasculature that are composed of ectatic or aberrant venous channels deficient in smooth muscle cells.

    Archives of Dermatology (Dermatology) - Fri, 4 December 2009
    http://archderm.ama-assn.org/

  • Psoriasis: Find relief for your symptoms

    Psoriasis — Comprehensive overview covers causes, symptoms and treatments of this chronic skin disorder.

    MayoClinic.com (Dermatology) - Fri, 6 November 2009
    http://www.mayoclinic.com

  • Acne: Causes, treatment and prevention

    Acne — Comprehensive overview covers causes, acne treatments, including adult acne treatments, and prevention.

    MayoClinic.com (Dermatology) - Fri, 6 November 2009
    http://www.mayoclinic.com

  • A Glimpse of Future Management of Melanoma

    The modern techniques of lymphatic mapping and sentinel node (SN) biopsy (LM/SNB) were introduced for the management of cutaneous melanoma in 19921 and quickly found wide acceptance. They have also been applied to the management of squamous carcinoma of various sites, Merkel cell carcinoma, breast cancer, cancer of the upper and lower gastrointestinal tract, and gynecological malignant neoplasms.2 The presence or absence of metastatic melanoma in the SN provides optimal staging and is the most accurate available indicator of prognosis.

    Archives of Dermatology (Dermatology) - Mon, 26 October 2009
    http://archderm.ama-assn.org/

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