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The U.S. Food and Drug Administration today approved a sterile, injectable gel to treat fecal incontinence in patients for whom other therapies such as diet change, fiber therapy or anti-motility medications failed. The gel is injected into a layer of tissue beneath the anus lining and may help build tissue in that area. By growing the surrounding tissue, the opening of the anus narrows and the patient may be able to better control those muscles.
Food and Drug Administration (Coloproctology) - Mon, 30 May 2011
http://www.fda.gov
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Colonoscopy is not a procedure associated with frequent risks of severe complications and the most frequent disadvantages are connected with the subject’s older age or with the endoscopic removal of intestinal polyps. In order to verify these associations, the data from CORI (Clinical Outcomes Research Initiative) national database, containing the endoscopic history of 18,271 patients followed for 30 days after the performance of a colonoscopy, have been examined.
MedNews (Coloproctology) - Mon, 18 April 2011
http://mn.medsurfnews.com/
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Injection of a bulking agent in the anal canal is an increasingly used treatment for faecal incontinence, but efficacy has not been shown in a controlled trial. To assess the efficacy of injection of dextranomer in stabilised hyaluronic acid (NASHA Dx) for treatment of faecal incontinence, a randomised, double-blind, sham-controlled trial was performed. Results showed that anal injection of NASHA Dx is an effective treatment for faecal incontinence, even if a refinement of selection criteria for patients, optimum injected dose, ideal site of injection, and long-term results might further increase the acceptance of this minimally invasive treatment.
The Lancet (Coloproctology) - Mon, 21 March 2011
http://www.thelancet.com
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Blood tests that indicate prostate-specific antigen (PSA) levels are rising rapidly over time are of little use in detecting aggressive prostate cancer and should not be done, a new study indicates. The study found that PSA velocity doesn't add any useful information beyond what physicians can already tell from other methods of prostate cancer screening, including the one-time PSA level test and digital rectal exams. Results are leading to hypotize the presence of many unnecessary biopsies, due to compliance to current screening guidelines that recommend biopsies for men who have high PSA velocity but no other signs of prostate cancer -- such as a suspected abnormality during a digital rectal exam or high PSA level during a single test.
Medline Plus (Coloproctology) - Tue, 1 March 2011
http://www.nlm.nih.gov/medlineplus
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IBS patients' brains are on high alert with less control of emotion and pain.
Medscape (Coloproctology) - Mon, 26 July 2010
http://www.medscape.com
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Given the immeasurable human distress and health care burden associated with intestinal failure, medical therapies aimed at intestinal rehabilitation are needed. Following massive small-bowel resection, the residual intestine is known to adapt structurally and functionally in an attempt to compensate for the resected portion. However, parenteral nutrition may be associated with many short- and long-term complications, including prevention of intestinal adaptation and promotion of mucosal atrophy due to lack of stimulus provided by oral or enteral nutrition. However, data herein demonstrate that the addition of butyrate, a short-chain fatty acid produced in the colon by dietary fiber fermentation, stimulates intestinal adaptation when added to parenteral nutrition, indicating that current solutions could be formulated to optimize intestinal adaptation and to reduce dependence of individuals with intestinal failure receiving long-term parenteral nutrition regimens.
Archives of Surgery (Coloproctology) - Wed, 23 June 2010
http://archsurg.ama-assn.org/
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Faecal incontinence is the involuntary loss of stool or flatus. It is a distressing condition that can have a substantially negative effect on quality of life. According to a systematic review it may affect 11-15% of the population.
British Medical Journal (Coloproctology) - Wed, 16 June 2010
http://www.bmjjournals.com
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A colonoscopy or a rectoscopy performed for rectal bleedings often put in evidence the presence of internal hemorrhoids, treated with electrocoagulation or infrared photocoagulation. Another option is rubber band ligation, but this procedure implies a great amount of pain, an easy bleeding and, sometimes, infectious complications.
MedNews (Coloproctology) - Tue, 18 May 2010
http://mn.medsurfnews.com/
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Video-colonoscopy through a little camera introduced into a capsule certainly represents a less invasive method than traditional colonoscopy to reveal colic lesions, so the procedure is more and more improved in order to avoid false negatives due to tool defects. A video camera has been recently used, with an automatic stand-by in order to specifically display colon and it has been tested in a prospective, international trial, sponsored by pharmaceutical industry, performed on 328 patients averagely 59.
MedNews (Coloproctology) - Mon, 1 March 2010
http://mn.medsurfnews.com/
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CT colonography, inappropriately defined by someone as “virtual colonoscopy”, has been, up to now, evaluated as a screening means in trials concerning above all populations with a high risk of intestinal cancer. In this European trial, 937 subjects with a high risk for tumours (family history for colorectal cancer, personal history of colorectal adenomas, positive occult blood test) have undergone CT colono-graphy followed, in the same day, by colonoscopy; endoscopists performed endoscopy in blind, which was abolished only in case of results contrasting with CT and endoscopy. The searched main outcome was the presence of an adenoma of at least 6 mm of diameter, with suspected characteristics. Compared with colonoscopy, CT colonography presented a positive predictive value of 62% and a negative pre-dictive value of 96%.
MedNews (Coloproctology) - Thu, 17 December 2009
http://mn.medsurfnews.com/