-
Ovarian stimulation to achieve multiple follicle development has been an integral part of IVF treatment. In the context of improved laboratory performance, the need for a large number of oocytes as an integral part of a successful IVF programme may be questioned. The aim of the current debate is to summarize the studies performed during the last decade to develop the concept of mild stimulation aiming to obtain fewer than eight oocytes. Here we examine the balance between IVF success and patient discomfort, and complications and cost, and how these might improve by simpler ovarian stimulation protocols aimed at retrieving fewer oocytes. We intend to analyse why progress has been rather slow and why there is much resistance to mild stimulation. Finally, presumed useful directions for future research will be discussed.
Human Reproduction - Mon, 18 October 2010
http://humrep.oupjournals.org/
-
The purpose of the present study was to review existing population surveys on the prevalence of infertility and proportion of couples seeking medical help for fertility problems.
Human Reproduction - Tue, 29 May 2007
http://humrep.oupjournals.org/
-
An association has been proposed between polycystic ovary syndrome (PCOS) and pregnancy-induced hypertensive disorders. Ambulatory blood pressure and carotid artery elasticity were therefore prospectively investigated in matched PCOS and control pregnancies.
Human Reproduction - Tue, 29 May 2007
http://humrep.oupjournals.org/
-
The Reprostat Steering Committee asks for the best monitors of reproductive health. In many European countries, some deleterious agents have caused declines over the past half-century in both dizygotic (DZ) twinning rates and sperm counts.
Human Reproduction - Tue, 24 April 2007
http://humrep.oupjournals.org/
-
The object of this review was to compare metformin versus oral contraceptive pill (OCP) treatment in polycystic ovary syndrome.
Human Reproduction - Tue, 24 April 2007
http://humrep.oupjournals.org/
-
It has been proposed that the human endometrium may contain a population of adult stem cells that are responsible for its remarkable regenerative capability.
Human Reproduction - Tue, 24 April 2007
http://humrep.oupjournals.org/
-
Uterine lymphoid cell repertoires are specialized in order to meet the twin demands of successful pregnancy and local immunosurveillance. The possibility that some of these populations might differentiate locally from progenitor cells has been proposed.
Human Reproduction - Thu, 12 April 2007
http://humrep.oupjournals.org/
-
Excessive fibrosis is frequently associated with endometriosis. To evaluate the involvement of the extracellular matrix contractility of endometriotic stromal cells (ECSCs) in the pathogenesis of endometriosis-associated fibrosis, we compared the collagen gel contractility of cultured ECSCs with that of normal endometrial stromal cells.
Human Reproduction - Thu, 12 April 2007
http://humrep.oupjournals.org/
-
Female infertility can be caused by scarring and occlusion of the Fallopian tubes. Sexually transmitted bacteria can damage the delicate epithelial layer of human Fallopian tubes (HFT).
Human Reproduction - Thu, 12 April 2007
http://humrep.oupjournals.org/