Researchers have analyzed past studies to investigate possible associations between maternal age and autism spectrum disorder. While much research has been done to identify potential genetic causes of autism, the current analysis suggests that non-heritable and environmental factors may also play a role in children's risk for autism.
Karolinska Institutet (Neurology) - Wed, 2 May 2012
A team of scientists from Johns Hopkins and elsewhere have developed nano-devices that successfully cross the brain-blood barrier and deliver a drug that tames brain-damaging inflammation in rabbits with cerebral palsy. For the study, researchers used tiny, manmade molecules laced with N-acetyl-L-cysteine (NAC), an anti-inflammatory drug used as antidote in acetaminophen poisoning. The researchers precision-targeted brain cells gone awry to halt brain injury. In doing so they improved the animals’ neurologic function and motor skills.
Johns Hopkins Hospital (Neurology) - Tue, 24 April 2012
In patients suffering from migraine and tension-type headache, in general tricyclic agents are prescribed, even if antidepressants market has been occupied almost entirely by more recent drugs, like SSRIs. In order to compare their efficacy, a meta-analysis has been performed on 37 randomized studies involving about 3200 people (averagely 40 years of age; 73% females) and lasted averagely 10 weeks; the studies had been performed to compare the efficacy of tricyclic agents with placebo, with SSRIs and with beta-blockers in the treatment of migraine and of tension-type headache.
MedNews (Neurology) - Mon, 23 April 2012
Based on their clinical experience and observations, a team of Johns Hopkins physicians and psychologists concluded that more than one-third of the patients admitted to The Johns Hopkins Hospital’s inpatient epilepsy monitoring unit for treatment of intractable seizures have been discovered to have stress-triggered symptoms rather than a true seizure disorder.
Johns Hopkins Hospital (Neurology) - Tue, 17 April 2012
A new study suggests that injections of steroids or arthritis drugs in the spine may not provide much extra relief for people with chronic back and leg pain due to nerve damage.
Reuters (Neurology) - Tue, 17 April 2012
According to many epidemiological studies, we know that the increase in plasmatic homocysteine is associated with a decrease in cognitive functions, so researchers consequently wondered whether vitamin B supplementation, capable to decrease the levels of homocysteine, can avoid or delay cognitive decrease.
MedNews (Neurology) - Tue, 10 April 2012
Researchers have discovered that there are a number of drugs that give cognitive function a boost. These drugs could help fuel our understanding of cognitive disorders, including Alzheimer's disease.
Health-EU (Neurology) - Tue, 20 March 2012
Distinct patterns of activity — which may indicate a predisposition to care for infants — appear in the brains of adults who view an image of an infant face — even when the child is not theirs, according to a study by researchers at the National Institutes of Health and in Germany, Italy, and Japan. Seeing images of infant faces appeared to activate in the adult's brains circuits that reflect preparation for movement and speech as well as feelings of reward. The findings raise the possibility that studying this activity will yield insights not only into the caregiver response, but also when the response fails, such as in instances of child neglect or abuse.
National Institutes of Health (Neurology) - Tue, 20 March 2012
In order to verify whether a relationship exists between the use of antiplatelet agents and brain hemorrhage, some researchers have performed a meta-analysis on 25 cohort studies involving 9900 patients struck by brain hemorrhage; at the moment of the cerebrovascular event, 23% of these subjects was under a continuative therapy with an antiplatelet agent.
MedNews (Neurology) - Mon, 19 March 2012
Irish researchers have made new strides in the treatment of Huntington's disease by identifying an enzyme linked with genetic mutations associated with the condition. The enzymes identified by the scientists in this new study are called histone deacetylase complexes (HDACs). When HDACs are active, they exacerbate the disease-causing mutation in cells, which the researchers believe contributes to the severity of the disorder. When the team inhibited the HDACs with experimental drugs the risk of further mutation was significantly lower.
Cordis - Community Research and Development Information Service (Neurology) - Tue, 6 March 2012