Toxicology

Opioid Side Effects — Mechanism-Based Therapy

Opioid analgesics generate numerous side effects that complicate their use in postoperative care, in the treatment of sickle cell vaso-occlusive episodes, and in the treatment of pain associated with advanced cancer and other life-shortening illnesses.
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 http://content.nejm.org/cgi/content/short/358/22/2400?rss=1&...

New England Journal of Medicine