Orthopaedics

Bisphosphonates and Atypical Fractures

In some trials, atypical hip fractures (subtrochanteric ones or at metaphysis) have been remarked after long-term treatments with bisphosphonates, pleading, as a physiopathological explanation, an excess in the suppression of bone turnover. But in these trials, it was impossible to establish a cause-effect relation, so some researchers have now examined the frequency of these fractures in three trials previously published and concerning randomized trials on osteoporosis therapy with bisphosphonates.
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 http://mn.medsurfnews.com/contents/en/5896/display/bisphosph...

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