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Oncology
The Women's Health Initiative trial of estrogen plus progestin, compared with a placebo, in postmenopausal women was stopped in 2002 because the health risks exceeded the benefits of hormone therapy. Within the first year of follow-up after discontinuation of hormonal therapy, the risk of breast cancer declined sharply.
New England Journal of Medicine - Fri, 6 February 2009
http://www.nejm.org
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Pediatrics
In this prospective, population-based survey of children under the age of 5 years, respiratory syncytial virus (RSV) was shown to be associated with 20% of hospitalizations, 18% of emergency department visits, and 15% of office visits for acute respiratory infections during the winter. Only 3% of the outpatient RSV infections were specifically diagnosed.
New England Journal of Medicine - Fri, 6 February 2009
http://www.nejm.org
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Oncology
The largest study so far has found no convincing association between use of these drugs and an increase in the risk for ovarian cancer.
Medscape - Fri, 6 February 2009
http://www.medscape.com
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Cardiology
Current use of moderate to high doses of statins for patients hospitalized with sepsis was associated with a mortality risk reduction of more than 20%.
Medscape - Fri, 6 February 2009
http://www.medscape.com
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Dermatology
Vectical Ointment, a first-of-its-kind topical vitamin D3 ointment, uses a naturally occurring, active form of vitamin D3 to treat psoriasis and is safe for use in sensitive skin areas.
Medscape - Fri, 6 February 2009
http://www.medscape.com
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Neurology
Critically ill patients frequently require invasive monitoring and other support that can lead to anxiety, agitation, and pain.1 Use of sedation is essential for the comfort and safety of these patients.
Journal of the American Medical Association - Fri, 6 February 2009
http://jama.ama-assn.org/
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Cardiology
Interest in the use of computed tomography (CT) for cardiac evaluation has increased rapidly since the introduction of 64-slice scanners. Reflecting this, the installation base of CT scanners in US cardiology practices has tripled in the past 2 years.1
Journal of the American Medical Association - Fri, 6 February 2009
http://jama.ama-assn.org/
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Rheumatology
A new practice guideline from the American Academy of Orthopaedic Surgeons (AAOS) underscores recent research showing that some commonly used treatments for osteoarthritis (OA) of the knee lack any strong support from scientific evidence.
Journal of the American Medical Association - Fri, 6 February 2009
http://jama.ama-assn.org/
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Infectious Diseases
Two teams of scientists say they have found a key area of the H5N1 bird flu virus which seems to be vital to the virus' ability to copy itself, and hope the discovery could lead to new drugs to fight the virus.
CNN.com - Fri, 6 February 2009
http://www.cnn.com
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Infectious Diseases
The Bill and Melinda Gates Foundation and private business have separately pledged new funds to combat, respectively, neglected tropical diseases and malaria.
British Medical Journal - Fri, 6 February 2009
http://www.bmjjournals.com