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  • Genetics e Rare diseases

    Novel genes 'notch' glucose into place

    A novel gene called rumi regulates Notch signaling by adding a glucose molecule to the part of the Notch protein that extends outside a cell.

    Baylor College of Medicine - Wed, 30 January 2008
    http://www.bcm.edu

  • General medicine

    Contingent Workers and Contingent Health

    Employment arrangements in which the worker has a nontraditional relationship with the work-site employer have come to be grouped together in recent years as "contingent" work.

    Journal of the American Medical Association - Wed, 30 January 2008
    http://jama.ama-assn.org/

  • Pediatrics

    The Genetics Revolution and Primary Care Pediatrics

    Exploring a person's genome will enable clinicians to characterize health and disease states by molecular fingerprints, elucidate mechanistic pathways, and develop new preventive, diagnostic, and therapeutic strategies.

    Journal of the American Medical Association - Wed, 30 January 2008
    http://jama.ama-assn.org/

  • Toxicology

    Cannabinoids for chronic pain

    Evidence of the effectiveness of cannabinoids is strong for treating cancer, central pain, and spasticity related pain; the evidence is mixed for treating acute pain and weak for treating peripheral neuropathic pain.

    British Medical Journal - Wed, 30 January 2008
    http://www.bmjjournals.com

  • Nephrology

    Chronic kidney disease in pregnancy

    Pregnant women with chronic renal disease adapt poorly to a gestational increase in renal blood flow. This may accelerate their decline in renal function and lead to a poor pregnancy outcome.

    British Medical Journal - Wed, 30 January 2008
    http://www.bmjjournals.com

  • Diabetology

    Physician Counseling May Promote Healthier Lifestyle in Patients With Type 2 Diabetes

    A randomized controlled trial shows that during usual care visits, a brief physician intervention to promote discussion of behavioral goals leads to increased physical activity and weight loss.

    Medscape - Wed, 30 January 2008
    http://www.medscape.com

  • Oncology

    Multimodal Treatment May Help in Invasive Bladder Cancer

    A bladder sparing protocol is feasible in a selected population of patients with muscle-invasive bladder cancer who decline radical surgery, Italian researchers report in the January issue of Cancer.

    Medscape - Wed, 30 January 2008
    http://www.medscape.com

  • Cardiology

    NT-ProBNP Level Best Prognostic Indicator for Advanced Heart Failure

    New research indicates that the plasma level of NT-proBNP is a better prognostic indictor than the glomerular filtration rate (GFR) estimated with standard equations in patients with advanced heart failure.

    Medscape - Wed, 30 January 2008
    http://www.medscape.com

  • Allergology

    A few shots away: Immunotherapy may relieve allergy symptoms

    Those who suffer from allergic asthma, rhinitis, conjunctivitis or stinging insect allergies may be good candidates to receive immunotherapy, also known as "allergy shots".

    American Academy of Allergy, Asthma and Immunology - Wed, 30 January 2008
    http://www.aaaai.org

  • Psychiatry

    Elevated Fear Conditioning to Socially Relevant Unconditioned Stimuli in Social Anxiety Disorder

    Though conditioned fear has long been acknowledged as an important etiologic mechanism in social anxiety disorder, past psychophysiological experiments have found no differences in general conditionability among social anxiety patients using generally aversive but socially nonspecific unconditioned stimuli.

    American Journal of Psychiatry - Wed, 30 January 2008
    http://ajp.psychiatryonline.org/

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