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Cardiology
Although randomized studies have shown a beneficial effect of drug-eluting stents in reducing the risk of repeated revascularization, these trials were underpowered to compare rates of death and myocardial infarction. The long-term safety of drug-eluting stents has been questioned recently.
New England Journal of Medicine - Fri, 16 February 2007
http://www.nejm.org
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Cardiology
The safety of drug-eluting stents has been called into question by recent reports of increased stent thrombosis, myocardial infarction, and death. Such studies have been inconclusive because of their insufficient size, the use of historical controls, a limited duration of follow-up, and a lack of access to original source data.
New England Journal of Medicine - Fri, 16 February 2007
http://www.nejm.org
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Infectious Diseases
In early 2005, physicians at a rural hospital in KwaZulu-Natal, a province of South Africa, were concerned by a high rate of rapid death among patients infected with the human immunodeficiency virus (HIV) who also had tuberculosis.
New England Journal of Medicine - Fri, 16 February 2007
http://www.nejm.org
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Pediatrics
Children with Kawasaki disease are at risk for the development of coronary-artery aneurysms. Standard therapy for this disorder includes intravenous immune globulin and aspirin. This study shows that, as compared with placebo, the addition of a single pulsed dose of intravenous methylprednisolone has no further beneficial effect over that of standard therapy and therefore cannot be recommended for routine treatment.
New England Journal of Medicine - Fri, 16 February 2007
http://www.nejm.org
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Endocrinology
In this randomized trial of 39 patients with chronic pancreatitis and a distal obstruction of the pancreatic duct, surgical drainage was more effective at reducing pain than was endoscopic drainage.
New England Journal of Medicine - Fri, 16 February 2007
http://www.nejm.org
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General medicine
Il Consiglio dei Ministri ha approvato il "programma quadro" del Ministro della salute Livia Turco per la promozione di stili di vita in grado di contrastare, nel lungo periodo, il peso delle malattie croniche e far guadagnare anni di vita in salute ai cittadini.
Ministero della Salute - Fri, 16 February 2007
http://www.ministerosalute.it
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Pneumology
Whether local exposure to major roadways adversely affects lung-function growth during the period of rapid lung development that takes place between 10 and 18 years of age is unknown. This study investigated the association between residential exposure to traffic and 8-year lung-function growth.
The Lancet - Fri, 16 February 2007
http://www.thelancet.com
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Pediatrics
Higher maternal seafood consumption during pregnancy results in children showing better neurological function than children whose mothers eat low amounts or no seafood during pregnancy.
The Lancet - Fri, 16 February 2007
http://www.thelancet.com
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Oncology
Early improvements in disease-free survival have been noted when an aromatase inhibitor is given either instead of or sequentially after tamoxifen in postmenopausal women with oestrogen-receptor-positive early breast cancer.
The Lancet - Fri, 16 February 2007
http://www.thelancet.com
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Infectious Diseases
Vaccines will be one of the most important medical interventions for reducing morbidity and mortality in an influenza pandemic. The development of H5N1 vaccines to protect people in a pandemic is underway in several countries. But two disturbing problems about vaccine availability and accessibility exist.
The Lancet - Fri, 16 February 2007
http://www.thelancet.com