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  • General medicine

    Measuring the Impact of Medical Research: Moving From Outputs to Outcomes

    Billions of dollars are spent every year to support medical research, with a substantial percentage coming from charitable foundations. To justify these expenditures, some measure of the return on investment would be useful, particularly one aligned with the intended ultimate outcome of this scientific effort: the amelioration of disease.

    American Journal of Psychiatry - Tue, 6 February 2007
    http://ajp.psychiatryonline.org/

  • Psychiatry

    Physiologic Reactivity Despite Emotional Resilience Several Years After Direct Exposure to Terrorism

    Six and a half to 7 years after the 1995 terrorist bombing in Oklahoma City, the authors assessed autonomic reactivity to trauma reminders and psychiatric symptoms in adults who had some degree of direct exposure to the blast.

    American Journal of Psychiatry - Tue, 6 February 2007
    http://ajp.psychiatryonline.org/

  • Psychiatry

    Mood-Incongruent Psychotic Features in Bipolar Disorder

    Mood-incongruent psychotic features in bipolar disorder may signify a more severe form of the illness and might represent phenotypic manifestations of susceptibility genes shared with schizophrenia. This study attempts to characterize clinical correlates, familial aggregation, and genetic linkage in subjects with these features.

    American Journal of Psychiatry - Tue, 6 February 2007
    http://ajp.psychiatryonline.org/

  • Psychiatry

    Genetics of Recurrent Early-Onset Major Depression (GenRED)

    The authors carried out a genomewide linkage scan to identify chromosomal regions likely to contain genes that contribute to susceptibility to recurrent early-onset major depressive disorder, the form of the disorder with the greatest reported risk to relatives of index cases.

    American Journal of Psychiatry - Tue, 6 February 2007
    http://ajp.psychiatryonline.org/

  • Psychiatry

    A Randomized Controlled Clinical Trial of Psychoanalytic Psychotherapy for Panic Disorder

    The purpose of this study was to determine the efficacy of panic-focused psychodynamic psychotherapy relative to applied relaxation training, a credible psychotherapy comparison condition.

    American Journal of Psychiatry - Tue, 6 February 2007
    http://ajp.psychiatryonline.org/

  • Infectious Diseases

    Cellulose sulfate microbicide trial stopped

    A Phase III study of the candidate microbicide cellulose sulfate to prevent HIV transmission in women has been stopped prematurely because of a higher number of HIV infections in the active compared with the placebo group.

    World Health Organization - Sun, 4 February 2007
    http://www.who.int

  • Orthopaedics

    Targeted reinnervation for enhanced prosthetic arm function in a woman with a proximal amputation

    The function of current artificial arms is limited by inadequate control methods. We developed a technique that used nerve transfers to muscle to develop new electromyogram control signals and nerve transfers to skin, to provide a pathway for cutaneous sensory feedback to the missing hand.

    The Lancet - Sun, 4 February 2007
    http://www.thelancet.com

  • Andrology

    Sexual sequelae of general medical disorders

    That sexual symptoms can signal serious underlying disease confirms the importance of sexual enquiry as an integral component of medical assessment.

    The Lancet - Sun, 4 February 2007
    http://www.thelancet.com

  • Immunology

    Pneumococcal vaccination should substantially reduce child mortality

    Routine vaccination of infants against Streptococcus pneumoniae in the world’s poorest countries should substantially reduce childhood mortality. Pneumococcal vaccination was projected to prevent 262 000 of these deaths (7%) and avert 8.3 million DALYs annually.

    The Lancet - Sun, 4 February 2007
    http://www.thelancet.com

  • General medicine

    Capital punishment has no place in the 21st century

    Health professionals around the world should speak out against execution and use their influence to persuade the public and those in power that capital punishment is a cruel and senseless practice that has no place in the 21st century.

    The Lancet - Sun, 4 February 2007
    http://www.thelancet.com

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