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Neurology
To diagnose Alzheimer’s disease, doctors rule out several other conditions and recommend psychological testing.
MayoClinic.com - Tue, 5 December 2006
http://www.mayoclinic.com
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Oncology
A "super" form of the enzyme Akt1 could provide the key to boosting the effect of tumor vaccines by extending the lives of dendritic cells, the immune-system master switches that promote the response of T-cells, which attack tumors, said researchers at Baylor College of Medicine in a report that appears in the "advance online publication" section of the current issue of the journal Nature Biotechnology.
Baylor College of Medicine - Tue, 5 December 2006
http://www.bcm.edu
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Neurology
Treating obstructive sleep apnea may significantly reduce seizure frequency in patients with refractory epilepsy, a new pilot study suggests.
Medscape - Tue, 5 December 2006
http://www.medscape.com
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Infectious Diseases
A report by the world's leading international health organizations today calls for joint action to accelerate the development and licensing of a highly effective malaria vaccine.
World Health Organization - Tue, 5 December 2006
http://www.who.int
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Cardiology
While the role of hydroxymethyl glutaryl coenzyme A reductase inhibitors (statins) in secondary prevention of cardiovascular (CV) events and mortality is established, their value for primary prevention is less clear. To clarify the role of statins for patients without CV disease, we performed a meta-analysis of randomized controlled trials (RCTs).
Archives of Internal Medicine - Tue, 5 December 2006
http://archinte.ama-assn.org/
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Psychiatry
Depression is common in primary care but is suboptimally managed. Collaborative care, that is, structured care involving a greater role of nonmedical specialists to augment primary care, has emerged as a potentially effective candidate intervention to improve quality of primary care and patient outcomes.
Archives of Internal Medicine - Tue, 5 December 2006
http://archinte.ama-assn.org/
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Cardiology
Obesity is associated with increased risk of atrial fibrillation (AF), but it is unknown whether the association differs by duration or persistence of AF. It is also unknown to what extent cardiovascular risk factors may mediate this association.
Archives of Internal Medicine - Tue, 5 December 2006
http://archinte.ama-assn.org/
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General Surgery
For patients with lumbar disk herniation, the Spine Patient Outcomes Research Trial (SPORT) randomized trial intent-to-treat analysis showed small but not statistically significant differences in favor of diskectomy compared with usual care. However, the large numbers of patients who crossed over between assigned groups precluded any conclusions about the comparative effectiveness of operative therapy vs usual care.
Journal of the American Medical Association - Tue, 5 December 2006
http://jama.ama-assn.org/
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Ophthalmology
Children who are losing their eyesight could get help from a procedure normally used only in adults. Doctors at Baylor College of Medicine in Houston are testing a laser treatment, called photorefractive keratectomy, or PRK, on children to help reverse high refractive error, which consists of severe nearsightedness, farsightedness, or astigmatism.
Baylor College of Medicine - Tue, 5 December 2006
http://www.bcm.edu
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General medicine
The FDA has approved a urethral bulking agent (Macroplastique), a propylene mesh urethral sling (I-Stop TOMS), and a new indication for an excimer laser system (Nidek EC-5000).
Medscape - Tue, 5 December 2006
http://www.medscape.com