Oncology 

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  • Use of Gene Signatures to Improve Risk Estimation in Cancer

    Breast cancer is one of the most prevalent human cancers and ranks second as a cause of cancer death in women. In 2006, approximately 212 000 new cases of invasive breast cancer were diagnosed in the United States, and each year more than 40 000 women die of the disease.

    Journal of the American Medical Association (Oncology) - Fri, 4 April 2008
    http://jama.ama-assn.org/

  • Finasteride and Prostate Cancer

    The Prostate Cancer Prevention Trial (PCPT) was performed to assess whether finasteride is able to prevent prostate cancer.

    MedNews (Oncology) - Sat, 29 March 2008
    http://mn.medsurfnews.com/

  • Breast MRI scans 'overly scare'

    MRI scans on women with a high risk of breast cancer falsely spot tumours in most positive cases.

    BBC News (Oncology) - Thu, 27 March 2008
    http://news.bbc.co.uk

  • Molecular Origins of Cancer: Epigenetics in Cancer

    Classic genetics alone cannot explain the diversity of phenotypes within a population. Nor does classic genetics explain how, despite their identical DNA sequences, monozygotic twins or cloned animals can have different phenotypes and different susceptibilities to a disease. The concept of epigenetics offers a partial explanation of these phenomena.

    New England Journal of Medicine (Oncology) - Wed, 19 March 2008
    http://www.nejm.org

  • DNA Methylation Markers and Early Recurrence in Stage I Lung Cancer

    Despite optimal and early surgical treatment of non–small-cell lung cancer (NSCLC), many patients die of recurrent NSCLC. Scientists investigated the association between gene methylation and recurrence of the tumor.

    New England Journal of Medicine (Oncology) - Wed, 19 March 2008
    http://www.nejm.org

  • European guidelines for quality assurance in cervical cancer screening

    Cancer of the uterine cervix primarily affects younger women, with the majority of cases appearing between the ages of 35 and 50, when many women are actively involved in their careers or caring for their families.

    Health-EU (Oncology) - Thu, 13 March 2008
    http://ec.europa.eu/health-eu/index_en.htm

  • Interval in PSA Screening

    Two trials are in progress, an American one (PLCO) and a European one (ERSPC), in order to establish whether the PSA screening is able to decrease prostate cancer mortality.

    MedNews (Oncology) - Wed, 12 March 2008
    http://mn.medsurfnews.com/

  • Potent Brachytherapy Effective Against Vaginal Cancer

    High-dose rate brachytherapy (HDRB) appears effective for many patients with primary or recurrent cancer of the vagina, according to Pennsylvania-based researchers.

    Medscape (Oncology) - Wed, 5 March 2008
    http://www.medscape.com

  • Adjuvant Therapy for Surgically Resected Pancreatic Adenocarcinoma

    In 2008, approximately 37 000 patients will be diagnosed with pancreatic adenocarcinoma in the United States, and most of these patients will succumb to this disease within the first year following diagnosis. Only approximately 7400 patients will have localized cancer, usually involving the head of the pancreas, and are candidates for surgery if the tumor is resectable, as defined by the absence of vascular involvement.

    Journal of the American Medical Association (Oncology) - Wed, 5 March 2008
    http://jama.ama-assn.org/

  • Rituximab for the treatment of relapsed or refractory stage III or IV follicular non-Hodgkin's lymphoma

    The review and re-appraisal of the use of rituximab for the treatment of relapsed or refractory stage III or IV follicular non-Hodgkin's lymphoma has resulted in a change in the guidance.

    National Institute for Health and Clinical Excellence (Oncology) - Thu, 28 February 2008
    http://www.nice.org.uk

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