Ophthalmology

Prospective Study of Common Variants in the Retinoic Acid Receptor-Related Orphan Receptor {alpha} Gene and Risk of Neovascular Age-Related Macular Degeneration

Common variants and haplotypes within the RORA gene appear to act synergistically with the ARMS2 A69S polymorphism to increase risk of neovascular AMD. These data add further evidence of a high level of complexity linking genetic and modifiable risk factors to AMD development and should help efforts at risk prediction.
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 http://archopht.ama-assn.org/cgi/content/short/128/11/1462?r...

Archives of Ophthalmology