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Since aspirin has been used in low doses in cardiologic prevention, the frequency of complications for the digestive system has been increasing and the use of protonic pump inhibitors, if on one side can decrease aspirin-induced ulcers, on the other side reduces the efficacy of clopidogrel and invalidates the results in patients obliged to take both drugs in secondary prevention.
MedNews (Gastroenterology) - Mon, 1 March 2010
http://mn.medsurfnews.com/
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The use of imaging techniques (US and CT) in case of acute abdominal pain no doubts gives help but with high costs, without thinking to radiation exposure caused by CT. Through a Dutch multicentric and prospective trial, 1021 adults with abdominal pain of a duration between 2 hours and 5 days have been studied to determine the optimal diagnostic strategy.
MedNews (Gastroenterology) - Mon, 22 February 2010
http://mn.medsurfnews.com/
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A systematic review showed no link between recurrent abdominal pain and H pylori infection, and conflicting evidence for a link between epigastric pain and H pylori infection.
Medscape (Gastroenterology) - Mon, 22 February 2010
http://www.medscape.com
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Karolinska Institutet is coordinating a new research project to chart the molecular mechanisms used by our normal gut flora that affect our physiology of our body. This fascinating project goes by the name of Tornado and has been funded to the tune of SEK 62 million by the EU?s Seventh Framework Programme.
Karolinska Institutet (Gastroenterology) - Mon, 22 February 2010
http://ki.se/ki/jsp/polopoly.jsp?d=130&l=en
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In order to evaluate the costs/benefits relation in bariatric surgery, this observational prospective trial has been performed on the data from 33 American surgical centers, examining the data of 4610 patients undergoing bariatric surgeries from 2005 to 2007. Average BMI was of 46.5 and performed interventions were the following: 65% laparoscopic Roux-en-Y gastric bypass, 9% open Roux-en-Y bypass and 26% laparoscopic gastric bandage.
MedNews (Gastroenterology) - Fri, 12 February 2010
http://mn.medsurfnews.com/
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A 22 year old woman with a one year history of anorexia nervosa was admitted as an emergency after she collapsed. She was hypoglycaemic, with a blood glucose concentration of 1.5 mmol/l. Her hypoglycaemia was corrected, and, after discussion with her and her eating disorder specialist, she was transferred to the gastroenterology unit to start nasogastric refeeding. Her body mass index was 12.9.
British Medical Journal (Gastroenterology) - Fri, 12 February 2010
http://www.bmjjournals.com
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As Glass et al. discuss in their review article (Oct. 29 issue), norovirus is the major cause of epidemic gastroenteritis and the most common cause of diarrhea in adults. Prospective studies have shown that
3 to 36% of enteric infections lead to a new diagnosis of the irritable bowel syndrome, one of the most common gastrointestinal disorders seen in primary care and specialist practice. A recent meta-analysis of nine prospective cohort studies showed that intestinal infection was associated with an increase by a factor of six in the odds ratio for the irritable bowel syndrome.
New England Journal of Medicine (Gastroenterology) - Fri, 12 February 2010
http://www.nejm.org
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According to previously performed trials, it was hypothesized that the discontinuation of a protonic pump inhibitor (PPI) can cause a rebound of acid hyper secretion, due to an increase, provoked by the PPI, of plasmatic gastrin, which, in its turn, stimulates gastric cells. When the PPI is interrupted, these cells would undergo a stimulation and would increase the production of acid. In order to verify the clinical aspect of this phenomenon, some researchers in Denmark have performed a double-blind randomized trial involving 120 healthy volunteers with no previous event of dyspepsia and pyrosis: participants received a 12-week treatment with placebo or an 8-week treatment with esomeprazole (40 mg/die), followed by 4 weeks with placebo.
MedNews (Gastroenterology) - Mon, 1 February 2010
http://mn.medsurfnews.com/
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Rotavirus is the leading cause of gastroenteritis in children worldwide. In this report, the efficacy of the rotavirus vaccine among 4417 children in Malawi and South Africa was studied in a randomized trial. Severe rotavirus gastroenteritis occurred in 4.9% of the infants in the placebo group as compared with 1.9% of the infants in the pooled vaccine group; the vaccine efficacy was 61.2%.
New England Journal of Medicine (Gastroenterology) - Mon, 1 February 2010
http://www.nejm.org
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Laparoscopic total gastrectomy for advanced gastric cancer is an approach that has been developing since 1999, when it was first described by Azagra et al1 and Uyama et al.2 In this article, Shinohara et al show an expertise and technical skill with outcomes and lymphadenectomy comparable to those of open total gastrectomies.
Archives of Surgery (Gastroenterology) - Fri, 15 January 2010
http://archsurg.ama-assn.org/