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Biologicals are a relatively new class of medicines that carry specific risks (eg, immunogenicity). However, limited information is available on the nature and timing of safety problems with their use that were identified after approval.
Journal of the American Medical Association (Pharmacology) - Wed, 22 October 2008
http://jama.ama-assn.org/
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Using paracetomol in the first year of life, or in early childhood, is associated with an increased risk of asthma, rhinoconjunctivitis, and eczema at age 6-7 years.
The Lancet (Pharmacology) - Wed, 24 September 2008
http://www.thelancet.com
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With the marketing of newer and newer molecules, adverse reactions become frequent and among these, the particularly severe ones, too.
MedNews (Pharmacology) - Tue, 15 July 2008
http://mn.medsurfnews.com/
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In spite of aspirin use in secondary prevention, various patients with established cardiovascular disease have afterwards severe complications like infarction, ictus or death for cardiovascular cause.
MedNews (Pharmacology) - Fri, 20 June 2008
http://mn.medsurfnews.com/
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Recently, a meta-analysis relative to 9 trials (for an overall of 700 patients) has indicated the use of alpha- or calcium-antagonists to facilitate the passage of ureteral calculi.
MedNews (Pharmacology) - Wed, 16 April 2008
http://mn.medsurfnews.com/
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Minocycline has an anti-inflammatory effect which implied its use also in non-infectious diseases. In animal models, also for stroke there was its beneficial action, probably through the decrease of inflammation consequent to ischemia and apoptosis.
MedNews (Pharmacology) - Fri, 4 April 2008
http://mn.medsurfnews.com/
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The greatest public health benefit of advances in understanding the human genome may be realized for common chronic diseases such as cardiovascular disease, diabetes mellitus, and cancer. Attempts to integrate such knowledge into clinical practice are still in the early stages, and as a result, many questions surround the current state of this translation.
Journal of the American Medical Association (Pharmacology) - Wed, 19 March 2008
http://jama.ama-assn.org/
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Scientists at Karolinska Institutet have achieved new advances in the fight against cardiovascular disease. A new drug has been shown to reduce levels of harmful blood cholesterol in people, without producing the serious side-effects associated with previous medicines.
Karolinska Institutet (Pharmacology) - Wed, 2 January 2008
http://ki.se/ki/jsp/polopoly.jsp?d=130&l=en
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Il Consiglio dei Ministri ha approvato, su proposta dei Ministri della Salute Livia Turco e delle Politiche Europee Emma Bonino, un decreto legislativo che modifica la normativa che ha dato attuazione alla direttiva 2001/83 (decreto legislativo n. 219 del 2006) relativa a un codice comunitario sui medicinali per uso umano.
Ministero della Salute (Pharmacology) - Tue, 4 December 2007
http://www.ministerosalute.it
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According to a recent trial performed in the Netherlands (British Journal of Clinical Pharmacology 2007; 63:232), the interruption in the administration of some drugs in older patients with a history of accidental falls is capable to lower the relapse risk.
MedNews (Pharmacology) - Tue, 13 November 2007
http://mn.medsurfnews.com/