Pharmacology

Drug-Related Hyperkaliemia

The use of drugs interfering with the rennin-angiotensin system has become wider and wider, in recent years, with the marketing of ACE-inhibitors before and of ARB (sartans) afterwards. With such a high number it is easy to discover the birth of new interactions between drugs. Knowing that hyperkaliemia has been associated with the use of ACE-inhibitors and trimethoprim, a case-control trial has been performed in Toronto among subjects ≥ 66 years of age under continuative treatment with drugs inhibiting rennin-angiotensin system and administered with an antibiotic.
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