Hepatology

Pioglitazone and Vitamin E in NASH

We have not got a specific therapy for non-alcoholic steatohepatitis (NASH), since there are many trials on various substances, but most of them are not randomized or they have been too short or with endpoints of unclear efficacy. Now, a phase-III, multicentric, double-blinded trial has been performed on 247 non-diabetic patients affected by NASH and randomized to receive pioglitazone (30 mg/die), vitamin E (800 UI/die) or placebo, for an overall of 96 weeks.
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 http://mn.medsurfnews.com/contents/en/6019/display/pioglitaz...

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