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In adults with subclinical hypothyroidism (increased TSH and normal fT4), is the administration of thyroxine supplementation capable to improve cognitive function? In order to answer this question, an English trial has been performed where 94 subjects over 64 years of age with subclinical hypothyroidism have been treated with thyroxine (up to TSH normalization) or placebo.
MedNews (Endocrinology) - Mon, 31 October 2011
http://mn.medsurfnews.com/
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Since an American campaign for pharmaceutical information invites male subjects to address themselves to their general practitioner in the presence of low levels of testosterone, clearly promoting an “off label” use of this substance, as it were a sort of anti-age drug or, worse, a panacea, the Endocrine Society has updated its 2006 guidelines concerning the therapy for androgenic deficiency.
MedNews (Endocrinology) - Mon, 10 October 2011
http://mn.medsurfnews.com/
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By measuring the radioactive isotope carbon-14, scientists have revealed an association between lipid cell dysfunction and diseases such as obesity, diabetes and blood lipid disorders. The study, which is presented in the journal Nature, can lead to new approaches to combating metabolic diseases.
Karolinska Institutet (Endocrinology) - Tue, 4 October 2011
http://ki.se/ki/jsp/polopoly.jsp?d=130&l=en
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The proposal to use testosterone in very old subjects is still nowadays under discussion, so every now and then researchers perform trials which should clear up this matter but they only increase confusion. It is the case of these new three trials: in the first one, performed in Europe, in order to identify the groups of symptoms associated with testosterone levels in 3369 males between 40 and 79 years of age, some questionnaires have been given and measurements of total and free basal plasmatic testosterone have been performed.
MedNews (Endocrinology) - Mon, 19 September 2011
http://mn.medsurfnews.com/
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To systematically determine the impact of growth hormone therapy on adult height of children with idiopathic short stature, a systematic review of the Cochrane Central Register of Controlled Trials, Medline, and the bibliographic references from retrieved articles of randomised and non-randomised controlled trials from 1985 to April 2010 has been performed. The analysis showed that Growth hormone therapy in children with idiopathic short stature seems to be effective in partially reducing the deficit in height as adults, although the magnitude of effectiveness is on average less than that achieved in other conditions for which growth hormone is licensed. The individual response to therapy is highly variable, and additional studies are needed to identify the responders.
British Medical Journal (Endocrinology) - Mon, 14 March 2011
http://www.bmjjournals.com
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NICE recommends denosumab (Prolia) as a treatment option for certain postmenopausal women who are at increased risk of primary and secondary osteoporotic fractures if other treatments available on the NHS are unsuitable. Denosumab joins the range of treatments that NICE has already advised should be available on the NHS, to help stop a fracture from occurring in the first place, or to help women who have previously had a fracture.
National Institute for Health and Clinical Excellence (Endocrinology) - Tue, 2 November 2010
http://www.nice.org.uk
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An ingredient in dark chocolate could help diabetics reduce high cholesterol levels, a study claims.
BBC News (Endocrinology) - Mon, 18 October 2010
http://news.bbc.co.uk
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Researchers believe a new body scanner which measures body volume, rather than body mass, is more effective at identifying obesity.
BBC News (Endocrinology) - Wed, 13 October 2010
http://news.bbc.co.uk
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In a small, double-blind clinical trial, treating hypovitaminosis C improved the mood state of acutely hospitalized patients, the majority of whom had subnormal levels of vitamin C.
Medscape (Endocrinology) - Tue, 5 October 2010
http://www.medscape.com
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Beware: the numbers on the scale don't tell the full story. It's possible to be obese even if you're at a healthy weight, said an expert at Baylor College of Medicine.
Baylor College of Medicine (Endocrinology) - Mon, 27 September 2010
http://www.bcm.edu