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A small study by researchers at the Johns Hopkins Children’s Center and Duke University shows that eating higher doses of milk protein in the form of dry powder substantially outperforms lower-dose therapy — a few drops of liquid milk extract under the tongue — for treatment of food allergies.
Johns Hopkins Hospital (Allergology) - Tue, 13 December 2011
http://www.hopkinshospital.org
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The U.S. Food and Drug Administration (FDA) announced today a streamlined, integrated approach to effectively and rapidly respond to human and animal foodborne illness outbreaks: the FDA Coordinated Outbreak Response and Evaluation (CORE) Network. The CORE Network is comprised of a multi-disciplinary team of epidemiologists, veterinarians, microbiologists, environmental health specialists, emergency coordinators, and risk communications specialists. Working full-time on outbreak prevention and response at headquarters, the CORE is complemented by trained, experienced investigators in FDA field offices nationwide. CORE will coordinate closely with the Centers for Disease Control and Prevention (CDC), the U.S. Department of Agriculture (USDA), and state public health and agriculture agencies in human and animal foodborne illness outbreaks.
Food and Drug Administration (Allergology) - Tue, 20 September 2011
http://www.fda.gov
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In an upcoming issue of The Journal of Allergy and Clinical Immunology (JACI), Nicholson et al evaluated the effects of an anti-IL-13 blocking antibody compared with placebo on repeated nasal allergen challenge (NAC) responses in hay fever patients out of season. Nasal challenge models with serial non-invasive sampling have considerable potential to study the molecular basis of mucosal inflammatory responses. The authors conclude that nasal challenge models can also be used to predict responders and monitor effects of specific therapy for allergy and asthma.
American Academy of Allergy, Asthma and Immunology (Allergology) - Mon, 18 July 2011
http://www.aaaai.org
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In mild or moderate allergic rhinitis, endonasal steroids are advised as they are effective and with no side effects. Most patients affected by this disorder present however also ocular allergic manifestations, at the same time, so physicians often use oral anti-histamines prepared for conjunctival use. Through a trial sponsored by pharmaceutical industry, 429 patients affected by seasonal allergic rhinitis have been treated with a mometasone-based spray (200 μg in an only daily sprinkling) or with a placebo spray for an overall of 15 days.
MedNews (Allergology) - Mon, 11 July 2011
http://mn.medsurfnews.com/
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The relationship between breastfeeding and allergic diseases is a subject of debate. The possibility that this relationship may vary by individual genetic susceptibility has not been explored. In an upcoming issue of The Journal of Allergy and Clinical Immunology (JACI), Hong et al. examined the effect of breastfeeding and gene-breastfeeding interactions on food sensitization (FS) in 960 children from an inner-city U.S. prospective birth cohort. FS was defined as specific IgE ≥0.35 kUA/L to any of eight common food allergens.
American Academy of Allergy, Asthma and Immunology (Allergology) - Mon, 27 June 2011
http://www.aaaai.org
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Anaphylactic reactions to diphtheria, tetanus, and pertussis vaccines (DTaP and Tdap) are rare. In an upcoming issue of The Journal of Allergy and Clinical Immunology, Kattan et al report a case series of 8 children who presented to their food allergy referral center from 2007-10 with a history of anaphylaxis to booster doses of these vaccines.
American Academy of Allergy, Asthma and Immunology (Allergology) - Tue, 14 June 2011
http://www.aaaai.org
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A unique landmark study, that defines the long-term natural history of EoE and the key role of allergy, is an important set of findings suggesting that EoE morbidity is greater among patients with atopy. Taken one step further, data support the need for allergy testing among patients with EoE, as identifying patients with atopy will not only assist in dietary management, but will help identify those at greatest risk for persistent disease.
American Academy of Allergy, Asthma and Immunology (Allergology) - Tue, 14 June 2011
http://www.aaaai.org
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Food allergy is not a wide problem, since it concerns averagely 1%-2% of the American population, and so it has not been studied in all its practical aspects, yet. With a trial sponsored by NIH, a review has been performed on the trials about food allergy published from 1988 to 2009, finding severe methodological gaps and a not univocal definition of “food allergy”. The authors then make the following observations: The widely spread perception that food allergies are increasing has not been confirmed by any good-quality trials. Skin prick-test and the determination of specific IgE are sensitive exams, but they are a little specific: about 50% of subjects with a history of food allergy and positive tests result not to be affected by any food allergy.
MedNews (Allergology) - Mon, 13 June 2011
http://mn.medsurfnews.com/
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The American Academy of Allergy, Asthma & Immunology (AAAAI) and the American College of Allergy, Asthma & Immunology's (ACAAI) omalizumab joint task force (OJTF) has been monitoring omalizumab-associated anaphylaxis for the past 4 years. In the original report published in a recent issue of The Journal of Allergy and Clinical Immunology, the OJTF found that anaphylaxis occurred in approximately 0.09% of patients receiving omalizumab (an anti-asthma medication), with the majority of the reactions occurring within the first 2 hours after the first 3 injections.
American Academy of Allergy, Asthma and Immunology (Allergology) - Tue, 24 May 2011
http://www.aaaai.org
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Allergic sensitization to molds is a risk factor for asthma and asthma severity. Mold sensitization depends strongly on geographic conditions and environmental mold allergen exposure. Heritable factors contribute to mold sensitization as well, but to date, only very few studies investigated the role of genetic variants in mold sensitization. In an upcoming issue of The Journal of Allergy and Clinical Immunology, Smit et al. used data from 1,243 adults who participated in the French Epidemiological Study on the Genetics and Environment of Asthma (EGEA) follow up. Sensitization to some allergens (Aspergillus, Cladosporium herbarum, Alternaria alternata) was assessed by skin prick test.
American Academy of Allergy, Asthma and Immunology (Allergology) - Tue, 24 May 2011
http://www.aaaai.org