Allergology
Genetic variants contribute to mold allergen sensitization in adult asthma
Allergic sensitization to molds is a risk factor for asthma and asthma severity. Mold sensitization depends strongly on geographic conditions and environmental mold allergen exposure. Heritable factors contribute to mold sensitization as well, but to date, only very few studies investigated the role of genetic variants in mold sensitization. In an upcoming issue of The Journal of Allergy and Clinical Immunology, Smit et al. used data from 1,243 adults who participated in the French Epidemiological Study on the Genetics and Environment of Asthma (EGEA) follow up. Sensitization to some allergens (Aspergillus, Cladosporium herbarum, Alternaria alternata) was assessed by skin prick test.
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American Academy of Allergy, Asthma and Immunology